TRR 267 publication database
2023
Zawada D, Kornherr J, Meier A, Santamaria G, Dorn T, Nowak-Imialek M, Ortmann D, Zhang F, Lachmann M, Dressen M, Ortiz M, Mascetti V, Harmer S, Nobles M, Tinker A, De Angelis MT, Pedersen R, Grote P, Laugwitz KL, Moretti A, Goedel A (2023) Retinoic acid signaling modulation guides in vitro specification of human heart field-specific progenitor pools. Nature Communications, in press View
McKinsey T.A., Foo R., Anene-Nzelu C.G., Travers J.G., Vagnozzi R.J., Weber N., Thum T. (2023) Emerging epigenetic therapies of cardiac fibrosis and remodelling in heart failure: from basic mechanisms to early clinical development. Cardiovascular Research, 118(18), 3482-3498 View
Cynn E., Li D.Y., O’Reilly M.E., Wang Y., Bashore A.C., Jha A., Foulkes A.S., Zhang H., Winter H., Maegdefessel L., Yan H., Li M., Ross L., Xue C., Reilly M.P. (2023) Human Macrophage Long Intergenic Noncoding RNA, SIMALR, Suppresses Inflammatory Macrophage Apoptosis via NTN1 (Netrin-1). Arteriosclerosis, Thrombosis, and Vascular Biology, 43(2), 286-299 View
Boos F., Oo J.A., Warwick T., Günther S., Izquierdo Ponce J., Lopez M., Rafii D., Buchmann G., Pham M.D., Msheik Z.S., Li T., Seredinski S., Haydar S., Kashefiolasl S., Plate K.H., Behr R., Mietsch M., Krishnan J., Pullamsetti S.S., Bibli S.-I., Hinkel R., Baker A.H., Boon R.A., Schulz M.H., Wittig I., Miller F.J., Jr., Brandes R.P., Leisegang M.S. (2023) The endothelial-enriched lncRNA LINC00607 mediates angiogenic function. Basic Research in Cardiology, 118(1), art. no. 5 View
de Oliveira Freitas Machado C., Schafranek M., Brüggemann M., Hernández Cañás M.C., Keller M., Di Liddo A., Brezski A., Blümel N., Arnold B., Bremm A., Wittig I., Jaé N., McNicoll F., Dimmeler S., Zarnack K., Müller-McNicoll M. (2023) Poison cassette exon splicing of SRSF6 regulates nuclear speckle dispersal and the response to hypoxia. Nucleic Acids Research, 51(2), 870-890 View
Farina F.M., Weber C., Santovito D. (2023) The emerging landscape of non-conventional RNA functions in atherosclerosis. Atherosclerosis, in press View
Ding D., Braun T. (2023) A Tedious Journey: Cardiomyocyte Proliferation Requires More Than S-Phase Entry and Loss of Polyploidization. Circulation, 147(2), 154-157 View
2022
Wu F, Li X, Looso M, Liu H, Ding D, Günther S, Kuenne C, Liu S, Weissmann N, Boettger T, Atzberger A, Kolahian S, Renz H, Offermanns S, Gärtner U, Potente M, Zhoo Y, Yuan Y, Braun T (2022) Spurious transcription causing innate immune responses is prevented by 5-hydroxymethylcytosine. Nature Genetics View
Moggio A, Schunkert H, Kessler T, Sager HB (2022) Quo Vadis? Immunodynamics of Myeloid Cells after Myocardial Infarction. International Journal of Molecular Sciences, 23(24):15814 View
Aragam KG, Jiang T, Goel A, Kanoni S, Wolford BN, Atri DS, Weeks EM, Wang M, Hindy G, Zhou W, Grace C, Roselli C, Marston NA, Kamanu FK, Surakka I, Muñoz Venegas L, Sherliker P, Koyama S, Ishigaki K, Åsvold BO, Brown MR, Brumpton B, de Vries PS, Giannakopoulou O, Giardoglou P, Gudbjartsson DF, Güldener U, Ijlal Haider SM, Helgadottir A, Ibrahim M, Kastrati A, Kessler T, Kyriakou T, Konopka T, Li L, Ma L, Meitinger T, Mucha S, Munz M, Murgia F, Nielsen JB, Nöthen MM, Pang S, Reinberger T, Schnitzler G, Smedley D, Thorleifsson G, von Scheidt M, Ulirsch, JC, Biobank Japan, EPIC-CVD, Arnar DO, Burtt NP, Costanzo MC, Flannick J, Ito K, Jang D-K, Kamatani Y, Khera AV, Komuro I, Kullo IJ, Lotta LA, Nelson CP, Roberts R, Thorgeirsson G, Thorsteinsdottir U, Webb TR, Baras A, Björkegren JLM, Boerwinkle E, Dedoussis G, Holm H, Hveem K, Melander O, Morrison AC, Orho-Melander M, Rallidis LS, Ruusalepp A, Sabatine MS, Stefansson K, Zalloua P, Ellinor PT, Farrall M, Danesh J, Ruff CT, Finucane HT, Hopewell JC, Clarke R, Gupta RM, Erdmann J, Samani NJ, Schunkert H, Watkins H, Willer CJ, Deloukas P, Kathiresan S, Butterworth AS & The CARDIoGRAMplusC4D Consortium (2022) Discovery and systematic characterization of risk variants and genes for coronary artery disease in over a million participants. Nature Genetics, 54, 1803–1815 View
Lim C, Pratama MY, Rivera C, Silvestro M, Tsao PS, Maegdefessel L, Gallagher KA, Maldonado T, Ramkhelawon B (2022) Linking single nucleotide polymorphisms to signaling blueprints in abdominal aortic aneurysms. Scientific Reports 12: 20990 View
Lu D, Cushman S, Thum T, Bär C (2022) Gene Therapy and Cardiovascular Diseases. Advances in experimental medicine and biology, 1396, pp. 235-254 View
Oo JA, Pálfi K, Warwick T, Wittig I, Prieto-Garcia C, Matkovic V, Tomašković I, Boos F, Izquierdo Ponce J, Teichmann T, Petriukov K, Haydar S, Maegdefessel L, Wu Z, Pham MD, Krishnan J, Baker AH, Günther S, Ulrich HD, Dikic I, Leisegang MS, Brandes RP (2022) Long non-coding RNA PCAT19 safeguards DNA in quiescent endothelial cells by preventing uncontrolled phosphorylation of RPA2. Cell Reports, 41(7): 111670 View
Zhang T, Künne C, Ding D, Günther S, Guo X, Zhou Y, Yuan X, Braun, T (2022) Replication collisions induced by de-repressed S-phase transcription are connected with malignant transformation of adult stem cells. Nature Communications, 13, 6907 View
Lu D, Chaterjee S, Xiao K, Riedel I, Huang C-K, Costa A, Cushman S, Neufeldt D, Rode L, Schmidt A, Juchem M, Leonardy J, Büchler G, Blume J, Gern O-L, Kalinke U, Wen Tan WL, Foo R, Vink A, van Laake LW, van der Meer P, Bär C, Thum T (2022) A circular RNA derived from the insulin receptor locus protects against doxorubicin-induced cardiotoxicity. European Heart Journal 43, 4496-4511 View
Leisegang MS, Bains JK, Seredinski S, Oo JA, Krause NM, Kuo C-C, Günther S, Cetin NS, Warwick T, Cao C, Boos F, Izquierdo Ponce J, Haydar S, Bednarz R, Valasarajan C, Fuhrmann DC, Preussner J, Looso M, Pullamsetti SS, Schulz MH, Jonker HRA, Richter C, Rezende F, Gilsbach R, Pflüger-Müller B, Wittig I, Grummt I, Ribarska T, Costa IG, Schwalbe H, Brandes RP (2022) HIF1α-AS1 is a DNA:DNA:RNA triplex-forming lncRNA interacting with the HUSH complex. Nature Communications, 13, 6563 View
Drekolia M-K, Talyan S, Cordellini Emídio R, Boon RA, Guenther S, Looso M, Dumbović G, Bibli S-I (2022) Unravelling the impact of aging on the human endothelial lncRNA transcriptome. Frontiers in Genetics, 13, 1035380 View
Zhang F, Meier AB, Poch CM, Tian Q, Engelhardt S, Sinnecker D, Lipp P, Laugwitz KL, Moretti A, Dorn T (2022) High-throughput optical action potential recordings in hiPSC-derived cardiomyocytes with a genetically encoded voltage indicator in the AAVS1 locus. Frontiers in Cell and Developmental Biology, 10:1038867 View
Gimbel AT, Koziarek S, Theodorou K, Schulz JF, Stanicek L, Kremer V, Ali T, Günther S, Kumar S, Jo H, Hübner N, Maegdefessel L, Dimmeler S, van Heesch S, Boon RA (2022) Aging-regulated TUG1 is dispensable for endothelial cell function. PLOS One, 17(9), p. e0265160 View
Garcia-Gonzalez C, Dieterich C, Maroli G, Wiesnet M, Wietelmann A, Li X, Yuan X, Graumann J, Stellos K, Kubin T, Schneider A, Braun T (2022) ADAR1 Prevents Autoinflammatory Processes in the Heart Mediated by IRF7. Circulation Research, 131(7): 580-597 View
Pang S, Yengo L, Nelson CP, Bourier F, Zeng L, Li L, Kessler T, Erdmann J, Mägi R, Läll K, Metspalu A, Mueller-Myhsok B, Samani, NJ, Visscher PM, Schunkert H (2022) Genetic and modifiable risk factors combine multiplicatively in common disease. Clinical Research in Cardiology View
Jones AN, Graß C, Meininger I, Geerlof A, Klostermann M, Krappmann D, Sattler M (2022) Modulation of pre-mRNA structure by hnRNP proteins regulates alternative splicing of MALT1. Science Advances, Vol 8, Issue 31, art. no. Eabp9153 View
Brandes RP, Wittig I (2022) Calcium-Controlled Reactive Oxygen Species Afterburner Perpetuates Endothelial Damage After Radiation Therapy. Arteriosclerosis, Thrombosis, and Vascular Biology, 42(9), pp. 1137-1138 View
Mohr E, Thum T, Bär C (2022) Accelerating cardiovascular research: recent advances in translational 2D and 3D heart models. European Journal of Heart Failure View
Georgieva AM, Guo X, Bartkuhn M, Günther S, Künne C, Smolka C, Atzberger A, Gärtner U, Mamchaoui K, Bober E, Zhou Y, Yuan X, Braun T (2022) Inactivation of Sirt6 ameliorates muscular dystrophy in mdx mice by releasing suppression of utrophin expression. Nature Communication, 13, 4184 View
Kichi ZA, Natarelli L, Sadeghian S, Boroumand MA, Behmanesh M, Weber C (2022) Orphan GPR26 Counteracts Early Phases of Hyperglycemia-Mediated Monocyte Activation and Is Suppressed in Diabetic Patients. Biomedicines, 10(7):1736 View
Meyer-Lindemann U, Mauersberger C, Schmidt A-C, Moggio A, Hinterdobler J, Li X, Khangholi D, Hettwer J, Gräßer C, Dutsch A, Schunkert H, Kessler T, Sager HB (2022) Colchicine Impacts Leukocyte Trafficking in Atherosclerosis and Reduces Vascular Inflammation. Frontiers in Immunology, 13:898690 View
Kirchhof L, Fouani Y, Knau A, Aslan GS, Heumüller AW, Wittig I, Müller-McNicoll M, Dimmeler S, Jaé N (2022) The G3BP1-UPF1-Associated Long Non-Coding RNA CALA Regulates RNA Turnover in the Cytoplasm. Non-Coding RNA, 8, 49 View
Jones AN, Walbrun A, Falleroni F, Rief M, Sattler M (2022) Conformational Effects of a Cancer-Linked Mutation in Pri-miR-30c RNA. Journal of Molecular Biology, 167705 View
Kokot KE, Kneuer JM, John D, Rebs S, Möbius-Winkler MN, Müller M, Andritschke M, Gaul S, Sheikh BN, Haas J, Thiele H, Leuschner F, Dimmeler S, Streckfuß-Bömmecke K, Meder B, Laufs U, Boeckel JN (2022) Reduction of A-to-I RNA editing in the failing human heart regulates formation of circular RNAs. Basic Research in Cardiology, 117, 32 View
Laggerbauer B, Engelhardt S (2022) MicroRNAs as therapeutic targets in cardiovascular disease. Journal of Clinical Investigation, 132(11):e159179 View
Peng Y, Du J, Günther S, Guo X, Wang S, Schneider A, Zhu L, Braun T (2022) Mechano-signaling via Piezo1 prevents activation and p53-mediated senescence of muscle stem cells. Redox Biology, Volume 52, 102309, ISSN 2213-2317 View
Poch, C.M., Foo, K.S., De Angelis, M.T., Jennbacken, K., Santamaria, G., Bähr, A., Wang, Q., Reiter, F., Hornaschewitz, N., Zawada, D., Bozoglu, T., My, I., Meier, A., Dorn, T., Hege, S., Lehtinen, M. L., Tsoi, Y. L., Hovdal, D., Hyllner, J., Schwarz, S., Sudhop, S., Jurisch, V., Sini, M., Fellows, M. D., Cummings, M., Clarke, J., Baptista, R., Eroglu, E., Wolf, E., Klymiuk, N., Tomasi, R., Dendorfer, A., Gaspari, M., Parrotta, E., Cuda, G., Krane, M., Sinnecker, D., Hoppmann, P., Kupatt, ,C., Fritsche-Danielson, R., Moretti, A., Chien, K. R., Laugwitz, K. (2022) Migratory and anti-fibrotic programmes define the regenerative potential of human cardiac progenitors. Nature Cell Biology, 24, 659–671 View
Fouani, Y., Kirchhof, L., Stanicek, L., Luxán, G., Heumüller, A. W., Knau, A., Fischer, A., Devraj, K., John, D., Neumann, P., Bindereif, A., Boon, R. A., Liebner, S., Wittig, I., Mogler, C., Karimova, M., Dimmeler, S., Jaé, N. (2022) The splicing-regulatory lncRNA NTRAS sustains vascular integrity. EMBO Reports View
Costa, A., Cushman, S., Haubner, B.J., Derda, A. A., Thum, T., Bär, C. (2022) Neonatal injury models: integral tools to decipher the molecular basis of cardiac regeneration. Basic Research in Cardiology, 117, 26 View
Zhang, F., Meier, A. B., Sinnecker, D., Engelhardt, S., Lipp, P., Laugwitz, K.-L., Dorn, T., Moretti, A. (2022) Generation of heterozygous (MRli003-A-5) and homozygous (MRli003-A-6) voltage-sensing knock-in human iPSC lines by CRISPR/Cas9 editing of the AAVS1 locus. Stem Cell Research, Volume 61, 102785, ISSN 1873-5061 View
Makarewich, C. A., Thum, T. (2022) Exercise-Induced Long Noncoding RNAs As New Players in Cardiac Hypertrophy. Circulation, 145(16), pp. 1234-1237 View
Bei Y, Lu D, Bär C, Chatterjee S, Costa A, Riedel I, Mooren FC, Zhu Y, Hung Z, Wei M, Hu M, Liu Y, Yu P, Wang K, Thum T, Xiao J. (2022) MiR-486 attenuates cardiac ischemia/reperfusion injury and mediates the beneficial effect of exercise for myocardial protection. Molecular Therapy, 30 (4), pp. 1675-1691 View
Li, L., Chen, Z., von Scheidt, M., Li, S., Steiner, A., Güldener, U., Koplev, S., Ma, A., Hao, K., Pan, C., Lusis, A. J., Pang, S., Kessler, T., Ermel, R., Sukhavasi, K., Ruusalepp, A., Gagneur, J., Erdmann, J., Kovacic, J.C., Björkegren, J.L.M., Schunkert, H. (2022) Publisher Correction: Transcriptome-wide association study of coronary artery disease identifies novel susceptibility genes. Basic Research in Cardiology, 117, 19. View
Publisher correction
Zhang, F., Meier, A.B., Lipp, P., Laugwitz, K.-L., Dorn, T., Moretti, A. (2022) Generation of heterozygous (MRli003-A-3) and homozygous (MRli003-A-4) TRPM4 knockout human iPSC lines. Stem Cell Research, 60, art. no. 102731 View
Peters, L.J.F., Baaten, C.C.F.M.J., Maas, S.L., Lu, C., Nagy, M., Jooss, N.J., Bidzhekov, K., Santovito, D., Moreno-Andrés, D., Jankowski, J., Biessen, E.A.L., Döring, Y., Heemskerk, J.W.M., Weber, C., Kuijpers, M.J.E., van der Vorst, E.P.C. (2022) MicroRNA-26b Attenuates Platelet Adhesion and Aggregation in Mice. Biomedicines, 10, 983 View
le Noble, F., Kupatt, C. Interdependence of Angiogenesis and Arteriogenesis in Development and Disease (2022). International Journal of Molecular Sciences, 23(7):3879 View
González, A., Richards, A.M., de Boer, R.A., Thum, T., Arfsten, H., Hülsmann, M., Falcao-Pires, I., Díez, J., Foo, R.S., Chan, M.Y., Aimo, A., Anene-Nzelu, C.G., Abdelhamid, M., Adamopoulos, S., Anker, S.D., Belenkov, Y., Gal, T.B., Cohen-Solal, A., Böhm, M., Chioncel, O., Delgado, V., Emdin, M., Jankowska, E.A., Gustafsson, F., Hill, L., Jaarsma, T., Januzzi, J.L., Jhund, P.S., Lopatin, Y., Lund, L.H., Metra, M., Milicic, D., Moura, B., Mueller, C., Mullens, W., Núñez, J., Piepoli, M.F., Rakisheva, A., Ristić, A.D., Rossignol, P., Savarese, G., Tocchetti, C.G., Van Linthout, S., Volterrani, M., Seferovic, P., Rosano, G., Coats, A.J. and Bayés-Genís, A. (2022) Cardiac remodelling – Part 1: From cells and tissues to circulating biomarkers. A review from the Study Group on Biomarkers of the Heart Failure Association of the European Society of Cardiology. European Journal of Heart Failure View
Santovito, D., Weber, C. (2022) Non-canonical features of microRNAs: paradigms emerging from cardiovascular disease. Nature Reviews Cardiology View
Publisher correction
Engelhardt, S., Dimmeler, S., Heim, C., Bär, C., Böttger, T., Boon, R., Brandes, R. P., Braun, T., , Dueck, A., Gagneur, J., Grote, P., Holdt, L. M., Jaé, N., Krishnan, J., Kupatt, C., Laugwitz, K.-L., Leisegang, M. S., Maegdefessel, L., Meitinger, T., Moretti, A., Müller-McNicoll, M., Sattler, M., Schnieke, A., Schulz, M., Schunkert, H., Schwalbe, H., Teupser, D., Thum, T., Weber, C., Wittig, I., Zarnack, K. (2022) Noncoding RNA in the cardiovascular system: Collaborative research centre/transregio (SFB-TRR 267). Kardiologe, 16(2), pp. 100-108 View
Egea, V., Megens, R.T.A., Santovito, D., Wantha, S., Brandl, R., Siess, W., Khani, S., Soehnlein, O., Bartelt, A., Weber, C., Ries, C. (2022) Properties and fate of human mesenchymal stem cells upon miRNA let-7f-promoted recruitment to atherosclerotic plaques. Cardiovascular Research, 2022 View
Kreutzer, F.P., Meinecke, A., Mitzka. S., Hunkler, H.J., Hobuß, L., Abbas, N., Geffers, R., Weusthoff, J., Xiao, K., Jonigk, D.D., Fiedler, J., Thum T. (2022) Development and characterization of anti-fibrotic natural compound similars with improved effectivity. Basic Research in Cardiology, 117(1):9 View
Li, L., Chen, Z., von Scheidt, M., Li, S., Steiner, A., Güldener, U., Koplev, S., Ma, A., Hao, K., Pan, C., Lusis, A.J., Pang, S., Kessler, T., Ermel, R., Sukhavasi, K., Ruusalepp, A., Gagneur, J., Erdmann, J., Kovacic, J.C., Björkegren, J.L.M., Schunkert, H. (2022) Transcriptome-wide association study of coronary artery disease identifies novel susceptibility genes. Basic Research in Cardiology, 117, 6 View
Publisher correction
Natarelli, L., Weber, C. (2022) A Non‐Canonical Link between Non‐Coding RNAs and Cardiovascular Diseases. Biomedicines, 10(2) Art. no. 445 View
Sala, L., Leonov, V., Mura, M., Giannetti, F., Khudiakov, A., Moretti, A., Crotti, L., Gnecchi, M., Schwartz, P.J. (2022) Use of hiPSC-Derived Cardiomyocytes to Rule Out Proarrhythmic Effects of Drugs: The Case of Hydroxychloroquine in COVID-19. Frontiers in Physiology, 12, art. no. 730127 View
Meier, A.B., Raj Murthi, S., Rawat, H., Toepfer, C.N., Santamaria, G., Schmid, M., Mastantuono, E., Schwarzmayr, T., Berutti, R., Cleuziou, J., Ewert, P., Görlach, A., Klingel, K., Laugwitz, K.-L., Seidman, C.E., Seidman, J.G., Moretti, A., Wolf, C.M. (2022) Cell cycle defects underlie childhood-onset cardiomyopathy associated with Noonan syndrome. iScience, 25(1), art. no. 103596 View
Bozoglu, T., Lee, S., Ziegler, T., Jurisch, V., Maas, S., Baehr, A., Hinkel, R., Hoenig, A., Hariharan, A., Kim, C.I., Decker, S., Sami, H., Koppara, T., Oellinger, R., Müller, O.J., Frank, D., Megens, R., Nelson, P., Weber, C., Schnieke, A., Sperandio, M., Santamaria, G., Rad, R., Moretti, A., Laugwitz, K.-L., Soehnlein, O., Ogris, M., Kupatt, C. (2022) Endothelial Retargeting of AAV9 In Vivo. Advanced Science View
Esfandyari, D., Idrissou, B.M.G., Hennis, K., Avramopoulos, P., Dueck, A., El-Battrawy, I., Grüter, L., Meier, M.A., Näger, A.C., Ramanujam, D., Dorn, T., Meitinger, T., Hagl, C., Milting, H., Borggrefe, M., Fenske, S., Biel, M., Dendorfer, A., Sassi, Y., Moretti, A., Engelhardt, S. (2022) MicroRNA-365 regulates human cardiac action potential duration. Nature Communications, 13, 220 View
2021
de Boer, R.A., Heymans, S., Backs, J., Carrier, L., Coats, A.J., Dimmeler, S., Eschenhagen, T., Filippatos, G., Gepstein, L., Hulot, J.-S., Knöll, R., Kupatt, C., Linke, W.A., Seidman, C.E., Tocchetti, C.G., van der Velden, J., Walsh, R., Seferovic, P.M. and Thum, T. (2021) Targeted therapies in genetic dilated and hypertrophic cardiomyopathies: from molecular mechanisms to therapeutic targets. A position paper from the Heart Failure Association (HFA) and the Working Group on Myocardial Function of the European Society of Cardiology (ESC). European Journal of Heart Failure View
Lörchner, H., Adrian-Segarra, J.M., Waechter, C., Wagner, R., Góes, M.E., Brachmann, N., Sreenivasan, K., Wietelmann, A., Günther, S.; Doll, N., Braun, T.; Pöling, J. (2021) Concomitant Activation of OSM and LIF Receptor by a Dual-Specific hlOSM Variant Confers Cardioprotection after Myocardial Infarction in Mice. International Journal of Molecular Sciences, 23, 353 View
Kupatt, C., Bozoglu, T. (2021) Ryanodine Receptors Matter for Cardiac Function in Duchenne Muscular Dystrophy: Stability First. Journal of the American College of Cardiology 78(24), pp. 2454-2456 View
Yang, C., Starnecker, F., Pang, S., Chen, Z., Güldener, U., Li, L., Heinig, M., Schunkert, H. (2021) Polygenic risk for coronary artery disease in the Scottish and English population. BMC Cardiovascular Disorders, 21(1), art. no. 586 View
Kaneshige A., Kaji T., Lidan Zhang L., Saito H., Nakamura A., Kurosawa T., Ikemoto-Uezumi M., Tsujikawa K., Seno S., Hori M., Yasuyuki Saito Y., Matozaki T., Maehara K., Ohkawa Y., Potente M., Watanabe S., Braun T., Uezumi A., Fukada S. (2021) Relayed signaling between mesenchymal progenitors and muscle stem cells ensures adaptive stem cell response to increased mechanical load. Cell Stem Cell, S1934-5909(21)00451-3 View
Zhang, F., Meier, A.B., Laugwitz, K.-L., Dorn, T., Moretti, A. (2021) Generation of heterozygous (MRli003-A-1) and homozygous (MRli003-A-2) MYH10 knockout human iPSC lines. Stem Cell Research, Volume 57, 102612, ISSN 1873-5061 View
Hoepfner, J., Leonardy, J., Lu, D., Schmidt, K., H.J. Hunkler, Biß, S., Foinquinos, A., Xiao, K., Regalla, K., Ramanujam, D., Engelhardt, S., Bär, C., Thum, T., (2021) The long non-coding RNA NRON promotes the development of cardiac hypertrophy in the murine heart. Molecular Therapy, ISSN 1525-0016 View
Oo, J.A., Brandes, R.P. & Leisegang, M.S. (2021) Long non-coding RNAs: novel regulators of cellular physiology and function. Pflugers Arch – Eur J Physiol View
Heumüller, A.W., Jones, A.N., Mourão, A., Klangwart, M., Shi, C., Wittig, I., Fischer, A., Muhly Reinholz, M., Buchmann, G.K., Dieterich, C., Potente, M., Braun, T., Grote, P., Jaé, N., Sattler, M., Dimmeler, S. (2021) Locus-conserved circular RNA cZNF292 controls endothelial cell flow responses. Circulation Research, doi: 10.1161/CIRCRESAHA.121.320029 View
Hunkler, H.J., Groß, S., Thum, T., Bär, C. (2021) Non-coding RNAs-key regulators of reprogramming, pluripotency and cardiac cell specification with therapeutic perspective for heart regeneration. Cardiovascular Research, cvab335 (oct. 2021) View
Krane, M., Dreßen, M., Santamaria, G., My, I., Schneider, C.M., Dorn, T., Laue, S., Mastantuono, E., Berutti, R., Rawat, H., Gilsbach, R., Schneider, P., Lahm, H., Schwarz, S., Doppler, S.A., Paige, S., Puluca, N., Doll, S., Neb, I., Brade, T., Zhang, Z., Abou-Ajram, C., Northoff, B., Holdt, L.M., Sudhop, S., Sahara, M., Goedel, A., Dendorfer, A., Tjong, F. V.Y., Rijlaarsdam, M.E., Cleuziou, J., Lang, N., Kupatt, C., Bezzina, C., Lange, R., Bowles, N.E., Mann, M., Gelb, B.D., Crotti, L., Hein, L., Meitinger, T., Wu, S., Sinnecker, D., Gruber, P.J., Laugwitz, K.-L., Moretti, A. (2021), Sequential defects in cardiac lineage commitment and maturation cause hypoplastic left heart syndrome. Circulation, 144, pp. 1409–1428 View
Fasolo, F., Jin, H., Winski, G., Chernogubova, E., Pauli, J., Winter, H., Li, D.Y., Glukha, N., Bauer, S., Metschl, S., Wu, Z., Koschinsky, M.L., Reilly, M., Pelisek, J., Kempf, W., Eckstein, H.H., Soehnlein, O., Matic, L., Hedin, U., Bäcklund, A., Bergmark, C., Paloschi, V., Maegdefessel, L. (2021) Long Noncoding RNA MIAT Controls Advanced Atherosclerotic Lesion Formation and Plaque Destabilization. Circulation 144(19), pp. 1567-1583 View
Valussi, M., Besser, J., Wystub-Lis, K., Zukunft, S., Richter, M., Kubin, T., Boettger, T., Braun, T. (2021) Repression of Osmr and Fgfr1 by miR-1/133a prevents cardiomyocyte dedifferentiation and cell cycle entry in the adult heart. Science Advances 7(42), art. no. Eabi6648 View
Westerlund, A.M., Hawe, J.S., Heinig, M., Schunkert, H. (2021) Risk prediction of cardiovascular events by exploration of molecular data with explainable artificial intelligence. International Journal of Molecular Sciences, 22(19), art. no. 10291 View
Gäbel, G., Northoff, B.H., Balboa, A., Becirovic‐Agic, M., Petri, M., Busch, A., Mägdefessel, L., Mahlmann, A., Ludwig, S., Teupser, D., de Waard, V., Golledge, J., Wanhainen, A., Wågsäter, D., Holdt, L.M., Lindeman, J.H.N. (2021) Parallel murine and human aortic wall genomics reveals metabolic reprogramming as key driver of abdominal aortic aneurysm progression. Journal of the American Heart Association, 10(17), art. no. E020231 View
Richter, C., Hohmann, K.F., Toews, S., Mathieu, D., Altincekic, N., Bains, J.K., Binas, O., Ceylan, B., Duchardt-Ferner, E., Ferner, J., Fürtig, B., Grün, J.T., Hengesbach, M., Hymon, D., Jonker, H.R.A., Knezic, B., Korn, S.M., Landgraf, T., Löhr, F., Peter, S.A., Pyper, D.J., Qureshi, N.S., Schlundt, A., Schnieders, R., Stirnal, E., Sudakov, A., Vögele, J., Weigand, J.E., Wirmer-Bartoschek, J., Witt, K., Wöhnert, J., Schwalbe, H., Wacker, A. (2021) 1H, 13C and 15N assignment of stem-loop SL1 from the 5′-UTR of SARS-CoV-2. Biomol NMR Assign View
Chen, Z., Schunkert, H. (2021) Genetics of coronary artery disease in the post-GWAS era. Journal of Internal Medicine View
Busch, A., Pauli, J., Winski, G., Bleichert, S., Chernogubova, E., Metschl , S., Winter, H., Trenner, M., Wiegering, A., Otto, C., Fischer, J., Reiser, J., Werner, J., Roy, J., Brostjan, C., Knappic, C., Eckstein, H., Paloschi, V., Maegdefessel, L. (2021) Lenvatinib halts aortic aneurysm growth by restoring smooth muscle cell contractility. JCI Insight, 6(15), art. no. e140364 View
Maletzko, A., Key, J., Wittig, I., Gispert, S., Koepf, G., Canet-Pons, J., Torres-Odio, S., West, A.P., Auburger, G. (2021) Increased presence of nuclear DNAJA3 and upregulation of cytosolic STAT1 and of nucleic acid sensors trigger innate immunity in the ClpP-null mouse. Neurogenetics View
Kessler, T., Schunkert, H. (2021) Coronary Artery Disease Genetics Enlightened by Genome-Wide Association Studies. JACC: Basic to Translational Science 6(7), pp. 610-623 View
Brandes, R.P., Gilsbach, R. (2021) Understanding Arteriosclerosis 2.0: Making Sense of Genetic Variants with scATAC. Circulation Research 129 (2), pp. 259-261 View
Hinkel, R., Batkai, S., Bähr, A., Bozoglu, T., Straub, S., Borchert, T., Viereck, J., Howe, A., Hornaschewitz, N., Oberberger, L., Jurisch, V., Kozlik-Feldmann, R., Freudenthal, F., Ziegler, T., Weber, C., Sperandio, M., Engelhardt, S., Laugwitz, K.L., Moretti, A., Klymiuk, N., Thum, T., Kupatt, C. (2021) AntimiR-132 Attenuates Myocardial Hypertrophy in an Animal Model of Percutaneous Aortic Constriction. Journal of the American College of Cardiology 77(23), 2923 View
Santovito, D., Weber, C. (2021) Not all myocardial infarctions are created equal: The potential of circulating microRNAs to discern coronary artery dissection. EBioMedicine 67, 103366 View
Zeng, L., Moser, S., Mirza-Schreiber, N., Lamina C., Coassin, S., Nelson, C.P., Annilo, T., Franzén, O., Kleber, M.E., Mack, S., Andlauer, T.F.M., Jiang, B., Stiller, B., Li, L., Willenborg, C., Munz M., Kessler, T., Kastrati, A., Laugwitz K.-L., Erdmann, J., Moebus, S., Nöthen, M.M. , Peters, A., Strauch, K., Müller-Nurasyid, M., Gieger, C., Meitinger, T., Steinhagen-Thiessen, E., März, W., Metspalu, A., Björkegren, J.L.M., Samani, N.J., Kronenberg, F., Müller-Myhsok, B., Schunkert, H. (2021) Cis-epistasis at the LPA locus and risk of cardiovascular diseases. Cardiovascular Research, cvab136 View
Lu, K., Seidel, T., Cao-Ehlker, X., Dorn, T., Nazeer Batcha, A.M., Schneider, C.M., Semmler, M., Volk, T., Moretti, A., Dendorfer, A., Tomasi, R. (2021) Progressive stretch enhances growth and maturation of 3D stem-cell-derived myocardium. Theranostics 11(13), 6138-6153. doi:10.7150/thno.54999 View
Natarelli, L., Parca, L., Mazza, T., Weber, C., Virgili, F., Fratantonio, D. (2021) MicroRNAs and Long Non-Coding RNAs as Potential Candidates to Target Specific Motifs of SARS-CoV-2. Non-coding RNA 7(1), 14 View
Monteiro, J.P., Rodor, J., Caudrillier, A., Scanlon, J.P., Spiroski, A.-M., Dudnakova, T., Pflüger-Müller, B., Shmakova, A., von Kriegsheim, A., Deng, L., Taylor R.S., Wilson-Kanamori, J.R., Chen, S.-H., Stewart, K., Thomson, A., Mitić, T., McClure, J.D., Iynikkel, J., Hadoke, P.W.F., Denby, L., Bradshaw, A.C., Caruso, P., Morrell, N.W., Kovacic, J.C., Ulitsky, I., Henderson, N.C., Caporali, A., Leisegang, M.S., Brandes, R.P. (2021) MIR503HG Loss Promotes Endothelial-to-Mesenchymal Transition in Vascular Disease. Circulation Research 128 (8), 1173-1190 View
Yuan, T., Krishnan, J. (2021) Non-coding RNAs in Cardiac Regeneration. Frontiers in Physiology 12, 650566 View
Mauersberger, C., Schunkert, H., Sager, H.B. (2021) Inflammation-Related Risk Loci in Genome-Wide Association Studies of Coronary Artery Disease. Cells 10(2), 440 View
Rieblinger, B., Sid, H., Duda, D., Bozoglu, T., Klinger, R., Schlickenrieder, A., Lengyel, K., Flisikowski, K., Flisikowska, T., Simm, N., Grodziecki, A., Perleberg, C., Bähr, A., Carrier, L., Kurome, M., Zakhartchenko, V., Kessler, B., Wolf, E., Kettler, L., Luksch, H., Hagag, I.T., Wise, D., Kaufmann, J., Kaufer, B.B., Kupatt, C., Schnieke, A., Schusser, B. (2021) Cas9-expressing chickens and pigs as resources for genome editing in livestock. PNAS 118(10), e2022562118 View
Stenton, S.L., Sheremet, N.L., Catarino, C.B., Andreeva,N.A., Assouline, Z., Barboni, P., Barel, O., Berutti, R., Bychkov, I., Caporali, L., Capristo, M., Carbonelli, M., Cascavilla, M.L., Issa, P.C., Freisinger, P., Gerber, S., Ghezzi, D., Graf, E., Heidler, J., Hempel, M., Heon, E., Itkis, Y.S., Javasky, E., Kaplan, J., Kopajtich, R., Kornblum, C., Kovacs-Nagy, R., Krylova, T.D., Kunz, W.S., La Morgia, C., Lamperti, C., Ludwig, C., Malacarne, P.F., Maresca, A., Mayr, J.A., Meisterknecht, J., Nevinitsyna, T.A., Palombo, F., Pode-Shakked, B., Shmelkova, M.S., Strom, T.M., Tagliavini, F., Tzadok, M., van der Ven, A., Vignal-Clermont, C., Wagner, M., Zakharova, E.Y., Zhorzholadze, N.V., Rozet, J.-M., Carelli, V., Tsygankova, P.G., Klopstock, T., Wittig, I., Prokisch, H. (2021) Impaired complex I repair causes recessive Leber’s hereditary optic neuropathy. Journal of Clinical Investigation131(6), e138267 View
Ramanujam, D., Schön, A.P., Beck, C., Vaccarello, P., Felician, G., Dueck, A., Esfandyari, D., Meister, G., Meitinger, T., Schulz, C., Engelhardt, S. (2021) MiR-21-Dependent Macrophage-to-Fibroblast Signaling Determines the Cardiac Response to Pressure Overload. Circulation doi:10.1161/CIRCULATIONAHA.120.050682 View
Santovito, D., Toto, L., De Nardis, V., Marcantonio, P., Dàloisio R., Mastropasqua, A., De Cesare, D., Bucci, M., Paganelli, C., Natarelli, L., Weber, C., Consolli, A., Mastropasqua, R., Cipollone, F. (2021) Plasma microRNA signature associated with retinopathy in patients with type 2 diabetes. Scientific Reports 11(1), 4136 View
Dobersch, S., Rubio, K., Singh, I., Günther, S., Graumann, J., Cordero, J., Castillo-Negrete, R., Bao Huynh, M.B., Mehta, A., Braubach, P., Cabrera-Fuentes, H., Bernhagen, J., Chao, C.-M., Bellusci, S., Günther, A., Preissner, K.T., Kugel, S., Dobreva, G., Wygrecka, M., Braun, T., Papy-Garcia, D., Barreto, G. (2021) Positioning of nucleosomes containing γ-H2AX precedes active DNA demethylation and transcription initiation. Nature Communications 12(1), 1072 View
Kupatt, C., Windisch, A., Moretti, A., Wolf, E., Wurst, W., Walter, M.C. (2021) Genome editing for Duchenne muscular dystrophy: a glimpse of the future? Gene Therapy, doi:10.1038/s41434-021-00222-4 View
Sonnenschein, K., Fiedler, J., de Gonzalo-Calvo, D., Xiao, K., Pfanne, A., Just, A., Zwadlo, C., Soltani, S., Bavendiek, U., Kraft, T., Remedios, C.D., Cebotari, S., Bauersachs, J., Thum, T. (2021) Blood-based protein profiling identifies serum protein c-KIT as a novel biomarker for hypertrophic cardiomyopathy. Scientific Reports 11(1), 1755 View
Pham, T.P., Bink, D.I., Stanicek, L., van Bergen, A., van Leeuwen, E., Tran, Y., Matic, L., Hedin, U., Wittig, I., Dimmeler, S., Boon, R.A. (2021) Long Non-coding RNA Aerrie Controls DNA Damage Repair via YBX1 to Maintain Endothelial Cell Function. Frontiers in Cell and Developmental Biology 8, 619079 View
2020
Winkler, M.J., Müller, P., Sharifi, A.M., Wobst, J., Winter, H., Mokry, M., Ma, L., van der Laan, S.W., Pang, S., Miritsch, B., Hinterdobler, J., Werner, J., Stiller, B., Güldener, U., Webb, T.R., Asselbergs, F.W., Björkegren, J.L.M., Maegdefessel, L., Schunkert, H., Sager, H.B., Kessler, T. (2020) Functional investigation of the coronary artery disease gene SVEP1. Basic Research in Cardiology 115, 67 View
Oo, J., Irmer, B., Günther, S., Warwick, T., Pálfi, K., Ponce, J.I., Teichmann, T., Pflüger-Müller, B., Gilsbach, R., Brandes, R.P., Leisegang, M.S. (2020) ZNF354C is a transcriptional repressor that inhibits endothelial angiogenic sprouting. Scientific Reports10, 19079 View
Hamid, S.M., Citir, M., Terzi, E.M., Cimen, I., Yildirim, Z., Dogan, A.E., Kocaturk, B., Onat, U.I., Arditi, M., Weber, C., Traynor-Kaplan, A., Schultz, C., Erbay, E. (2020) Inositol-requiring enzyme-1 regulates phosphoinositide signaling lipids and macrophage growth. EMBO Reports 21(12), e51462 View
Ali, T., Grote, P. (2020) Beyond the RNA-dependent function of LncRNA genes. eLife 9, e60583 View
Behjati Ardakani, F., Kattler, K., Heinen, T., Schmidt, F., Feuerborn, D., Gasparoni, G., Lepikhov, K., Nell, P., Hengstler, J., Walter, J., Schulz, M.H. (2020) Prediction of single-cell gene expression for transcription factor analysis. GigaScience 9(11), pp. 1-14 View
Santovito, D., Egea, V., Bidzhekov, K., Natarelli, L., Mourão, A., Blanchet, X., Wichapong, K., Aslani, M., Brunßen, C., Horckmans, M., Hristov, M., Geerlof, A., Lutgens, E., Daemen, M.J.A.P., Hackeng, T., Ries, C., Chavakis, T., Morawietz, H., Naumann, R., Von Hundelshausen, P., Steffens, S., Duchêne, J., Megens, R.T.A., Sattler, M., Weber, C. (2020) Autophagy unleashes noncanonical microRNA functions. Autophagy doi:10.1080/15548627.2020.1830523 View
Sumer, S.A., Hoffmann, S., Laue, S., Campbell, B., Raedecke, K., Frajs, V., Clauss, S., Kääb, S., Janssen, J.W.G., Jauch, A., Laugwitz, K.-L., Dorn, T., Moretti, A., Rappold, G.A. (2020) Precise Correction of Heterozygous SHOX2 Mutations in hiPSCs Derived from Patients with Atrial Fibrillation via Genome Editing and Sib Selection. Stem Cell Reports 15(4), pp. 999-1013 View
Schutt, C., Hallmann, A., Hachim, S., Klockner, I., Valussi, M., Atzberger, A., Graumann, J., Braun, T., Boettger, T. (2020) Linc-MYH configures INO80 to regulate muscle stem cell numbers and skeletal muscle hypertrophy. EMBO Journal, e105098 View
Lechner, K., Kessler, T., Schunkert, H. (2020) Should We Use Genetic Scores in the Determination of Treatment Strategies to Control Dyslipidemias? Current Cardiology Reports 22(11), 146 View
Zarnack, K., Balasubramanian, S., Gantier, M.P., Kunetsky, V., Kracht, M., Schmitz, M.L., Sträßer, K. (2020) Dynamic mRNP Remodeling in Response to Internal and External Stimuli. Biomolecules 10(9), 1310 View
Lu, D., Chatterjee, S., Xiao, K., Riedel, I., Wang, Y., Foo, R., Bär, C., Thum, T. (2020) MicroRNAs targeting the SARS-CoV-2 entry receptor ACE2 in cardiomyocytes. Journal of Molecular and Cellular Cardiology 148, pp. 46-49 View
Baehr, A., Umansky, K.B., Bassat, E., Jurisch, V., Klett, K., Bozoglu, T., Hornaschewitz, N., Solyanik, O., Kain, D., Ferraro, B., Cohen-Rabi, R., Krane, M., Cyran, C., Soehnlein, O., Laugwitz, K.L., Hinkel, R., Kupatt, C., Tzahor, E. (2020) Agrin Promotes Coordinated Therapeutic Processes Leading to Improved Cardiac Repair in Pigs. Circulation 142(9), pp. 868-881 View
Das, S., Shah, R., Dimmeler, S., Freedman, J.E., Holley, C., Lee, J.-M., Moore, K., Musunuru, K., Wang, D.-Z. , Xiao, J., Yin, K.-J. (2020) Noncoding RNAs in Cardiovascular Disease: Current Knowledge, Tools and Technologies for Investigation, and Future Directions: A Scientific Statement From the American Heart Association. Circulation. Genomic and Precision Medicine 13(4), p. e000062 View
Li, L., Pang, S., Zeng, L., Güldener, U., Schunkert, H. (2020) Genetically determined intelligence and coronary artery disease risk. Clinical Research in Cardiology doi:10.1007/s00392-020-01721-x View
Bär, C., Chatterjee, S., Falcão Pires, I., Rodrigues, P., Sluijter, J.P.G., Boon, R.A., Nevado, R.M., Andrés, V., Sansonetti, M., de Windt, L., Ciccarelli, M., Hamdani, N., Heymans, S., Figuinha Videira, R., Tocchetti, C.G., Giacca, M., Zacchigna, S., Engelhardt, S., Dimmeler, S., Madonna, R., Thum, T. (2020) Non-coding RNAs: update on mechanisms and therapeutic targets from the ESC Working Groups of Myocardial Function and Cellular Biology of the Heart. Cardiovascular Research 116(11), pp. 1805-1819 View
Eckstein, H.-H., Maegdefessel, L. (2020) Linking obesity with abdominal aortic aneurysm development. European Heart Journal 41(26), pp. 2469-2471 View
Peters, L.J.F., Biessen, E.A.L., Hohl, M., Weber, C., van der Vorst, E.P.C., Santovito, D. (2020) Small Things Matter: Relevance of MicroRNAs in Cardiovascular Disease. Frontiers in Physiology 11, 793 View
Jakobi, T., Siede, D., Eschenbach, J., Heumüller, A.W., Busch, M., Nietsch, R., Meder, B., Most, P., Dimmeler, S., Backs, J., Katus, H.A., Dieterich, C. (2020) Deep Characterization of Circular RNAs from Human Cardiovascular Cell Models and Cardiac Tissue. Cells 9(7), 1616 View
Santovito, D., Egea, V., Bidzhekov, K., Natarelli, L., Mourão, A., Blanchet, X., Wichapong, K., Aslani, M., Brunßen, C., Horckmans, M., Hristov, M., Geerlof, A., Lutgens, E., Daemen, M.J.A.P., Hackeng, T., Ries, C., Chavakis, T., Morawietz, H., Naumann, R., von Hundelshausen, P., Steffens, S., Duchêne, J., Megens, R.T.A., Sattler, M., Weber, C. (2020) Noncanonical inhibition of caspase-3 by a nuclear microRNA confers endothelial protection by autophagy in atherosclerosis. Science Translational Medicine 12(546), eaaz294 View
Stanicek, L., Lozano-Vidal, N., Bink, D.I., Hooglugt, A., Yao, W., Wittig, I., van Rijssel, J., van Buul, J.D., van Bergen, A., Klems, A., Ramms, A.S., Le Noble, F., Hofmenn, P., Szulcek, R., Wang, S.P., Offermanns, S., Ercanoglu, M.S., Kwon, H.-B., Stainier, D., Huveneers, S., Kurian, L., Dimmeler, S., Boon, R.A. (2020) Long non-coding RNA LASSIE regulates shear stress sensing and endothelial barrier function. Communications Biology 3(1), 265 View
Groß, S., Jahn, C., Cushman, S., Bär, C., Thum, T. (2020) SARS-CoV-2 receptor ACE2-dependent implications on the cardiovascular system: From basic science to clinical implications. Journal of Molecular and Cellular Cardiology 144, pp. 47-53 View
Trembinski, D.J., Bink, D.I., Theodorou, K., Sommer, J., Fischer, A., van Bergen, A., Kuo, C.-C., Ivan G. Costa, I.G., Schürmann, C., Leisegang, M.S., Brandes, R.P., Alekseeva, T., Brill, B., Wietelmann, A., Johnson, C.N., Spring-Connell, A., Kaulich, M., Werfel, S., Engelhardt, S., Hirt, M.N., Yorgan, K., Eschenhagen, T., Kirchhof, L., Hofmann, P., Jaé, N., Wittig, I., Hamdani, N., Bischof, C., Krishnan, J., Houtkooper, R.H., Dimmeler, S., Boon, R.A. (2020) Aging-regulated anti-apoptotic long non-coding RNA Sarrah augments recovery from acute myocardial infarction. Nature Communications 11(1), 2039 View
Jaé, N., Dimmeler, S. (2020) Noncoding RNAs in Vascular Diseases. Circulation Research 126, pp. 1127-1145 View
Hinkel, R., Ramanujam, D., Kaczmarek, V., Howe, A., Klett, K., Beck, C., Dueck, A., Thum, T., Laugwitz, K.-L., Maegdefessel, L., Weber, C., Kupatt, C., Engelhardt, S. (2020) AntimiR-21 Prevents Myocardial Dysfunction in a Pig Model of Ischemia/Reperfusion Injury. Journal of the American College of Cardiology 75(15), pp. 1788-1800 View
Brandes, R.P., Oo, J.A., Leisegang, M.S. (2020) Thymosin beta-4x LINCs SPAAR to its non-coding function. Cardiovascular Research 116(12), pp. 1927-1928 View
Baehr, A., Hinkel, R., Kupatt, C. (2020) Statins Make a Difference in Acute Myocardial Infarction: A Revival. Journal of the American College of Cardiology 75(12), pp. 1403-1405 View
Moretti, A., Fonteyne, L., Giesert, F., Hoppmann, P., Meier, A.B., Bozoglu, T., Baehr, A., Schneider, C.M., Sinnecker, D., Klett, K., Fröhlich, T., Abdel Rahman, F., Haufe, T., Sun, S., Jurisch, V., Kessler, B., Hinkel, R., Dirschinger, R., Martens, E., Jilek, C., Graf, A., Krebs, S., Santamaria, G., Kurome, M., Zakhartchenko, V., Campbell, B., Voelse, K., Wolf, A., Ziegler, T., Reichert, S., Lee, S., Flenkenthaler, F., Dorn, T., Jeremias, I., Blum, H., Dendorfer, A., Schnieke, A., Krause, S., Walter, M.C., Klymiuk, N., Laugwitz, K.-H., Wolf, E., Wurst, W., Kupatt, C. (2020) Somatic gene editing ameliorates skeletal and cardiac muscle failure in pig and human models of Duchenne muscular dystrophy. Nature Medicine 26(2), pp. 207-214 View
Vilades, D., Martínez-Camblor, P., Ferrero-Gregori, A., Bär, C., Lu, D., Xiao, K., Vea, À., Nasarre, L., Vega, J.S., Leta, R., Carreras, F., Thum, T., Llorente-Cortés, V., de Gonzalo-Calvo, D. (2020) Plasma circular RNA hsa_circ_0001445 and coronary artery disease: Performance as a biomarker. FASEB Journal 34(3), pp. 4403-4414 View
Wu, Z.-Y., Trenner, M., Boon, R.A., Spin, J.M., Maegdefessel, L. (2020) Long noncoding RNAs in key cellular processes involved in aortic aneurysm. Atherosclerosis 292, pp. 112-118 View
2019
Sonnenschein, K., Wilczek, A.L., de Gonzalo-Calvo, D., Pfanne, A., Derda, A.A., Zwadlo, C., Bavendiek, U., Bauersachs, J., Fiedler, J., Thum, T. (2019) Serum circular RNAs act as blood-based biomarkers for hypertrophic obstructive cardiomyopathy. Scientific Reports 9(1), 20350 View
Santer, L., Bär, C., Thum, T. (2019) Circular RNAs: A Novel Class of Functional RNA Molecules with a Therapeutic Perspective. Molecular Therapy 27(8), pp. 1350-1363 View